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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Mesenchymal stem cells and their secreted molecules predominantly ameliorate fulminant hepatic failure and chronic liver fibrosis in mice respectively

Fig. 8

Schema depicting mechanisms of MSC and MSC-CM therapy. MSCs and MSC-CM containing MSC-secreted soluble factors ameliorate TAA-induced acute liver injury and CCl4-induced chronic liver fibrosis by acting on hepatocytes, macrophages, CD4 + helper T lymphocytes, and HSCs, which have important roles during the pathogenesis of liver injury. muMSC: murine mesenchymal stem cell; M0: undifferentiated macrophage; M1: M1 macrophage; M2: M2 macrophage

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Journal of Translational Medicine

ISSN: 1479-5876

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