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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Mesenchymal stem cells and their secreted molecules predominantly ameliorate fulminant hepatic failure and chronic liver fibrosis in mice respectively

Fig. 3

MSC delivery decreases apoptosis and enhances hepatocellular proliferation in mice with liver failure. Liver sections from a TAA-stimulated and b CCl4-stimulated mice were stained by TUNEL (dark brown nuclei, large for hepatocytes) and counterstained with methyl green (light blue). Ki67 immunofluorescence staining of liver sections from c TAA-stimulated and d CCl4-stimulated mice.Quantification of TUNEL-positivity in e TAA-stimulated and f CCl4-stimulated livers. Quantification of Ki67-positivity in g TAA-stimulated and h CCl4-stimulated livers. Data are shown as mean ± standard error of the mean of 10 random high-power fields per mouse. *P < 0.05; **P < 0.01; ***P < 0.001

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