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Table 1 Phenotype analysis of MDM differentiated in the presence of TMVs. Percentages of positive cells (mean ± SD) in 5 independent cultures are presented

From: Colorectal cancer-derived microvesicles modulate differentiation of human monocytes to macrophages

Marker

Control MDM

MDM + TMV0d

MDM + TMV036d

MDM + TMV6d

TMVs from:

Caco-2

LoVo

SW620

SW480

Caco-2

LoVo

SW620

SW480

Caco-2

LoVo

SW620

SW480

HLADR

30 ± 18

46 ± 24

42 ± 20

38 ± 23

45 ± 23

45 ± 23

38 ± 14

29 ± 13

47 ± 20

15 ± 8

32 ± 16

15 ± 9

24 ± 17

CD80

3 ± 7

16 ± 17*

14 ± 14*

6 ± 7

41 ± 16*

14 ± 8*

24 ± 10*

10 ± 8

49 ± 18*

20 ± 19*

14 ± 9*

3 ± 3

26 ± 15*

CD86

56 ± 16

46 ± 9

51 ± 22

53 ± 19

27 ± 2*

43 ± 13*

54 ± 35

56 ± 19

18 ± 5*

81 ± 6*

72 ± 11*

67 ± 16

44 ± 17

CD36

79 ± 8

55 ± 7*

54 ± 11*

70 ± 10

63 ± 25

42 ± 9

46 ± 5*

66 ± 15

64 ± 17

71 ± 31

84 ± 8

81 ± 9

64 ± 25

CD163

15 ± 9

6 ± 1*

12 ± 4

6 ± 1*

3 ± 3*

6 ± 1*

11 ± 7

8 ± 3

4 ± 4*

24 ± 22

35 ± 12*

16 ± 16

6 ± 1*

CD206

48 ± 13

79 ± 16*

79 ± 12*

76 ± 21*

69 ± 6*

86 ± 6*

78 ± 11*

74 ± 25

73 ± 7*

62 ± 20

65 ± 17

65 ± 22

52 ± 7

CD115

10 ± 8

10 ± 7

11 ± 11

10 ± 7

17 ± 4

9 ± 4

9 ± 5

9 ± 4

9 ± 5

10 ± 9

6 ± 5

10 ± 9

3 ± 4

  1. The statistical significance of differences between groups were calculated with Mann–Whitney test and denoted by an asterisk (* p < 0.05)