From: Colorectal cancer-derived microvesicles modulate differentiation of human monocytes to macrophages
Marker | Control MDM | MDM + TMV0d | MDM + TMV036d | MDM + TMV6d | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TMVs from: | Caco-2 | LoVo | SW620 | SW480 | Caco-2 | LoVo | SW620 | SW480 | Caco-2 | LoVo | SW620 | SW480 | |
HLADR | 30 ± 18 | 46 ± 24 | 42 ± 20 | 38 ± 23 | 45 ± 23 | 45 ± 23 | 38 ± 14 | 29 ± 13 | 47 ± 20 | 15 ± 8 | 32 ± 16 | 15 ± 9 | 24 ± 17 |
CD80 | 3 ± 7 | 16 ± 17* | 14 ± 14* | 6 ± 7 | 41 ± 16* | 14 ± 8* | 24 ± 10* | 10 ± 8 | 49 ± 18* | 20 ± 19* | 14 ± 9* | 3 ± 3 | 26 ± 15* |
CD86 | 56 ± 16 | 46 ± 9 | 51 ± 22 | 53 ± 19 | 27 ± 2* | 43 ± 13* | 54 ± 35 | 56 ± 19 | 18 ± 5* | 81 ± 6* | 72 ± 11* | 67 ± 16 | 44 ± 17 |
CD36 | 79 ± 8 | 55 ± 7* | 54 ± 11* | 70 ± 10 | 63 ± 25 | 42 ± 9 | 46 ± 5* | 66 ± 15 | 64 ± 17 | 71 ± 31 | 84 ± 8 | 81 ± 9 | 64 ± 25 |
CD163 | 15 ± 9 | 6 ± 1* | 12 ± 4 | 6 ± 1* | 3 ± 3* | 6 ± 1* | 11 ± 7 | 8 ± 3 | 4 ± 4* | 24 ± 22 | 35 ± 12* | 16 ± 16 | 6 ± 1* |
CD206 | 48 ± 13 | 79 ± 16* | 79 ± 12* | 76 ± 21* | 69 ± 6* | 86 ± 6* | 78 ± 11* | 74 ± 25 | 73 ± 7* | 62 ± 20 | 65 ± 17 | 65 ± 22 | 52 ± 7 |
CD115 | 10 ± 8 | 10 ± 7 | 11 ± 11 | 10 ± 7 | 17 ± 4 | 9 ± 4 | 9 ± 5 | 9 ± 4 | 9 ± 5 | 10 ± 9 | 6 ± 5 | 10 ± 9 | 3 ± 4 |