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Table 1 Phenotype analysis of MDM differentiated in the presence of TMVs. Percentages of positive cells (mean ± SD) in 5 independent cultures are presented

From: Colorectal cancer-derived microvesicles modulate differentiation of human monocytes to macrophages

Marker Control MDM MDM + TMV0d MDM + TMV036d MDM + TMV6d
TMVs from: Caco-2 LoVo SW620 SW480 Caco-2 LoVo SW620 SW480 Caco-2 LoVo SW620 SW480
HLADR 30 ± 18 46 ± 24 42 ± 20 38 ± 23 45 ± 23 45 ± 23 38 ± 14 29 ± 13 47 ± 20 15 ± 8 32 ± 16 15 ± 9 24 ± 17
CD80 3 ± 7 16 ± 17* 14 ± 14* 6 ± 7 41 ± 16* 14 ± 8* 24 ± 10* 10 ± 8 49 ± 18* 20 ± 19* 14 ± 9* 3 ± 3 26 ± 15*
CD86 56 ± 16 46 ± 9 51 ± 22 53 ± 19 27 ± 2* 43 ± 13* 54 ± 35 56 ± 19 18 ± 5* 81 ± 6* 72 ± 11* 67 ± 16 44 ± 17
CD36 79 ± 8 55 ± 7* 54 ± 11* 70 ± 10 63 ± 25 42 ± 9 46 ± 5* 66 ± 15 64 ± 17 71 ± 31 84 ± 8 81 ± 9 64 ± 25
CD163 15 ± 9 6 ± 1* 12 ± 4 6 ± 1* 3 ± 3* 6 ± 1* 11 ± 7 8 ± 3 4 ± 4* 24 ± 22 35 ± 12* 16 ± 16 6 ± 1*
CD206 48 ± 13 79 ± 16* 79 ± 12* 76 ± 21* 69 ± 6* 86 ± 6* 78 ± 11* 74 ± 25 73 ± 7* 62 ± 20 65 ± 17 65 ± 22 52 ± 7
CD115 10 ± 8 10 ± 7 11 ± 11 10 ± 7 17 ± 4 9 ± 4 9 ± 5 9 ± 4 9 ± 5 10 ± 9 6 ± 5 10 ± 9 3 ± 4
  1. The statistical significance of differences between groups were calculated with Mann–Whitney test and denoted by an asterisk (* p < 0.05)