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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells

Fig. 6

CD24 expression is relative with the low degree differentiation of malignant gastric cancer and has a positive correlation with EGFR. The IRS is calculated as intensity of the staining reaction multiplied by the percentage of positive cells. Based on the IRS values, CD24 and EGFR were scored as weak, medium and strong in the following parts. a High and low degree differentiated malignant gastric cancer tissue sections were stained against CD24. Brown, CD24; Blue, haematoxylin. b IRS scores of CD24 according to tumor histological grade. c High and low degree differentiated malignant gastric cancer tissue sections were stained against EGFR. Brown, EGFR; Blue, haematoxylin. d IRS scores of EGFR according to tumor histological grade. e Using serial sections of the same sample, representative high and low degree differentiated malignant gastric cancer tissue stained for CD24 and EGFR are shown. f The scatterplot of correlated protein levels between CD24 and EGFR in high and low degree differentiated malignant gastric cancer tissue (n = 41). Scale bar 100 μm

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