Fig. 3
From: CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells
Downregulation of CD24 alters the localization and degradation of EGFR. a The mRNA levels of CD24 and EGFR were detected by qPCR in SGC-7901 cells transfected with control siRNA or siCD24. b and c The level of EGFR on cellular membrane of SGC-7901 cells (b) and BGC-823 cells (c) was measured using flow cytometry. d Representative immunofluorescence images of SGC-7901 cells transfected with control siRNA or siCD24 staining for EGFR and phalliodin. Scale bar 10 μM. Asterisk P < 0.05 in the siCD24 cells relative to siRNA control cells