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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: CD24 associates with EGFR and supports EGF/EGFR signaling via RhoA in gastric cancer cells

Fig. 2

Effects of siCD24 on EGFR downstream proteins and cell migration. a SGC-7901 cells transfected with control siRNA or siCD24, and protein levels of EGFR, P-ERK, ERK, P-Akt, Akt and E-cadherin were examined. b Representative immunofluorescence images of SGC-7901 cells transfected with control siRNA or siCD24 stained for E-cadherin. Scale bar, 10 μm. c A representative of wound healing assays in SGC-7901 cells transfected with control siRNA or siCD24 is presented, and the quantification of cell migration rate was performed. Data are presented as mean ± SD of 8 determinations asterisk P < 0.05 in the siCD24 cells relative to siRNA control cells. d Control and siCD24 SGC-7901 Cell migration rate was also evaluated by Transwell migration assay. Data are presented as mean ± SD of 3 determinations asterisk P < 0.05 in the siCD24 cells relative to control cells

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