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Table 2 Abnormal functional connectivity of bilateral ACC in BQD individuals compared with healthy controls

From: Betel quid dependence is associated with functional connectivity changes of the anterior cingulate cortex: a resting-state fMRI study

Brain region BA Voxels Maximal t
value
MNI coordinates
X Y Z
Left ACC
 Pons   61 5.23 −6 −27 −33
 L. caudate   38 4.26 −12 3 12
 L. thalamus   53 3.44 −6 −18 12
 R. thalamus   51 3.37 9 −21 9
 Midbrain   43 2.98 −6 −12 −12
 Cerebellum posterior lobe   27 3.10 −42 −57 −36
 vmPFC, ACC 47 424 −4.5 15 30 −9
 L. precuneus 7 32 −3.68 −15 −57 57
 L. parahippocampal/hypothalamus   33 −3.36 −12 0 −18
Right ACC
 Pons   114 5.87 −6 −24 −36
 L. caudate   43 4.90 −12 3 12
 R. caudate   41 3.45 15 15 9
 L. thalamus   117 3.95 −6 −18 12
 R. thalamus   64 3.91 18 −9 6
 Midbrain   88 4.18 6 −9 −9
 L. cerebellum posterior lobe   49 4.07 −36 −66 −33
 Cerebellum anterior lobe   62 3.87 6 −60 −30
 R. cerebellum posterior lobe   53 3.73 30 −66 −36
 mPFC, ACC 32.47 461 −4.47 18 27 −27
 L. precuneus 7 24 −3.80 −15 −57 60
 hypothalamus/parahippocampal_L   24 −3.35 3 0 −15
  1. A corrected threshold of P < 0.01 determined by Monte Carlo simulation was taken as meaning that there was a significant difference between groups
  2. L left, R right, mPFC medial prefrontal cortex, ACC anterior cingulate cortex, BA Brodmann’s area, MNI montreal neurological institute, x, y, z coordinates of primary peak locations in the MNI space