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Table 2 Mean urinary (±SD) concentrations of biomarkers assessed by Multi-Array and commercial ELISA assays in cohort #1

From: A multiplex immunoassay for the non-invasive detection of bladder cancer

  Multi-Array® Commercial ELISA
Total bladder cancer (n = 29) Total controls (n = 33) p value Total bladder cancer (n = 29) Total controls (n = 33) p value
IL8 (pg/ml) 1429.3 ± 2897.7 123.1 ± 510.2 <0.0001 1155.7 ± 2179.7 33.3 ± 45.1 <0.0001
MMP9 (ng/ml) 24.4 ± 64.2 3.2 ± 10.6 <0.0001 4.8 ± 4.1 0.9 ± 1.4 <0.00001
A1AT (ng/ml) 4968.0 ± 8965.9 412.9 ± 513.9 0.0004 2362.2 ± 3682.4 218.8 ± 593.6 <0.0001
ANG (pg/ml) 8487.6 ± 25,979.1 816.3 ± 947.4 0.004 538.5 ± 863.9 174.0 ± 210.8 0.016
VEGFA (pg/ml) 357.7 ± 437.6 306.7 ± 467.9 0.481 294.5 ± 795.4 166.3 ± 137.5 0.631
CA9 (pg/ml) 35.9 ± 63.6 15.4 ± 22.6 0.828 2.3 ± 0.0 2.3 ± 0.0 1.000
MMP10 (pg/ml) 112.7 ± 196.9 26.1 ± 64.8 0.002 12.2 ± 43.7 4.1 ± 0.0 0.301
APOE (pg/ml) 210,368.9 ± 758,136.6 7316.1 ± 11,258.8 0.016 46,241.4 ± 38,121.7 30,000.0 ± 0.0 0.001
PAI1 (ng/ml) 5.2 ± 13.7 0.2 ± 1.0 <0.0001 0.1 ± 0.1 0.1 ± 0.0 0.065
SDC1 (pg/ml) 10,393.9 ± 12,279.5 13,477.3 ± 10,745.7 0.204 53,545.5 ± 98,390.1 103,803.3 ± 108,345.5 0.0001