Fig. 6
From: Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathway
Overexpression of HMGA2 promote TSCC epithelial–mesenchymal transition (EMT) by upregulating Snail. a Immunohistochemitry analysis detecting the expression of HMGA2 and EMT markers (E-Cadherin, Vimentin and Snail) in abnormal tongue tissues and primary tongue tumor tissues with different histological differentiation. b Immunohistochemical staining showing the high expression and co-localization of HMGA2 and Snail in metastatic lymph node. c The correlation analysis showing the positive correlation between HMGA2 and Snail in TSCC patients