Fig. 5
From: Obesity inhibits the osteogenic differentiation of human adipose-derived stem cells
Calvarial defects treated with lnASC- or obASCs-seeded scaffolds display reduced osteoclastic activity. Calvarial defects were created in the parietal bone of nude mice. Histology was conducted 2 weeks post operatively. a Representative images of sections stained with TRAP, allowing osteoclasts to appear bright red. b Quantification of TRAP stain. Bars, ± SEM. ***, P < 0.001, compared to defects treated with neither scaffolds or cells; #, P < 0.05, compared between defects treated with scaffold and scaffolds seeded with lnASCs