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Table 2 Example of translational research—assistive device helping blind people to see with the aid of audio and haptic inputs

From: Translational research—the need of a new bioethics approach

Phase

Aims

Tasks

T0

Identifying the way sensory inputs overlay at the brain level

1. Neuroscience

2. Prospective/observational studies

T1

Developing audio and haptic sensors

Developing software to aid the translation of audio and haptic sensors to visual inputs or aids

3. Proof of concept

4. IT development

T2

Studying the usefulness of the device

Measuring neural/sensory inputs/outputs

5. Using beta testers in closed/open environments (NOT research subjects)

6. Possible medical research (bio-feedback)

T3

Disseminating the results to patients and clinicians

7. Certification of the device (analysis of the riskbenefit ratio)—might be needed a clinical trial

8. Increase awareness about the technology (marketing)

9. Promote the technology to stakeholders

10. Comparing the effectiveness of the technology with others at a population level, identifying possible limitations/adverse reactions

T4

Changing public health policies and behaviors beyond the effects of the treatment

11. Shift from intervention to prevention (public health campaigns, recommendations about lifestyle changes based on the results obtained from the previous phases)

T5

Social policies

12. Decreasing societal disparities, improving access to healthcare for underdeveloped communities, interacting with cities in order to maximize the input

  1. The completion of each preceding task is needed for the development of the next task
  2. Italic emphasized tasks are biomedical; non-emphasized tasks have a significant non-biomedical component