Fig. 3

PEBP and NBJ decreased the formation of mammospheres in cell culture. Mammospheres formation of 4T1 (a), MDAMB-231 (b), and MCF-7 (c) cells after treatment with either 100 or 150 μM GAE (gallic acid equivalent) of either polyphenol-enriched blueberry preparation (PEBP) or normal blueberry juice (NBJ) for 4–7 days and IL-6 production by 4T1 (d), MDAMB-231 (e), and MCF-7 (f) cells after treatment with 150 μM GAE of PEBP or NBJ for 6 and 24 h. All values are means of 4 separated experiments ±SEM. Bars that have no letter in common are significantly different from each other (p ≤ 0.05)