Fig. 4

Effects of kefir administration on ROS contribution to the endothelial dysfunction in SHR. Dose–response curves to acetylcholine-induced relaxations of aortic rings from SHR-kefir compared to the non-treated SHR and to the normotensive Wistar rats after the pre-blockade with apocynin (a). The bar graphs show the difference in the area under the curve (b) and the maximum relaxation (c) in response to acetylcholine. The values are the mean ± SEM (n = 7–8 animals per group)