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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Autoantibody signatures defined by serological proteome analysis in sera from patients with cholangiocarcinoma

Fig. 6

Coomassie-blue stained gels of 2D-resolved proteins from five tumour-affected CC livers. Each tumour extract was tested with serum from the corresponding patient (C, E, K, P and S). Arrows (CT, ET, KT, PT and ST) indicate the immunoreactive proteins that were only stained by CC sera. They are listed in Additional file 1: Table S1. Widespread immunoreactive spots were noted, depending on the CC serum tested. Of the 39 different proteins recognized by the CC sera, only nine were reactive with more than one-third of sera (Table 1). Serotransferrin was identified by 100 % of the five CC sera, actin by four (80 %), and ATP synthase subunit-α and α-enolase were each stained by three (60 %) of the CC sera. Some proteins were immunoreactive with two CC sera (40 %): annexin A2, A4 and A5, proteosome subunit-α type-2 and serum albumin

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