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Table 1 Plasma markers assessed in the post hoc analysis

From: Changes in plasma biomarkers following treatment with cabozantinib in metastatic castration-resistant prostate cancer: a post hoc analysis of an extension cohort of a phase II trial

Hypoxia-related markers Signaling pathways Inflammation Bone-related markers Micro-environment/angiogenesis
Marker Ref. Marker Ref. Marker Ref. Marker Ref. Marker Ref.
CA9 [34] VEGFA-VEGFR2 [14] CRP [35] BSAP [12] TIMP-2 [36]
GLUT1 [37] HGF-
c-MET
[7, 10, 16] IL-6 [38] SEMA3C [39] IL-8 [40, 41]
Clusterin [42] FLT3-FLT3L [18]   Trap5B [43] Thrombo-spondin-1 [44]
Caveolin [45] IGF1R-IGFI/IGFII [20, 46, 47]   ANG2-TIE2 [48, 18]
Osteopontin [49] AXL-GAS6 [30, 10, 16]  
  SCF [18]