Fig. 4

Effects of TLR2 ligands on mRNA expression of Th17/22 cytokines from PBMCs in AD patients. PBMCs were incubated with PGN or Pam3CSK4 for 8 h. IL-17A (a), IL-17F (b) and IL-22 (c) mRNA expression from PBMCs was determined by qPCR. Data were shown as 2^−ΔΔCt ± SEM. T-test was employed to compare the significant difference between AD patients and healthy individuals. *p < 0.05, **p < 0.01