Fig. 6
From: Interactions of tumour-derived micro(nano)vesicles with human gastric cancer cells
TMV effect on the GC1415 tumour growth and angiogenesis in NOD SCID mice. Before engrafting into NOD SCID mice GC1415 cells were or not exposed to TMV in vitro. Kinetic curve of tumour growth of cells exposed (or not) to TMV for 2 h (a) and 24 h (b). Angiogenesis as assessed quantitatively by haemoglobin content (c). Bars represent the mean ± SD from three experiments. Angiogenesis visualised as Matrigel plugs photos (d) and histological analysis (e). i-cells alone, ii-cells + TMV after 2 h incubation, iii- cells alone and iv- cells + TMV after 24 h pre-exposure. *Significantly different (p < 0.01) in comparison to control