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Table 2 Pattern and frequency mutations and polymorphisms with potential impact on INIs reduced susceptibility of INIs among HIV-1 subtype C (n = 45)

From: Lack of integrase inhibitors associated resistance mutations among HIV-1C isolates

Minor INI-resistance mutations

Frequencey

L74 M

1 (2.2)

L74Ia

4 (8.8)

T97A

2 (4.4)

E138Xa

4 (8.8)

G163Ea

6 (13.3)

G163 Va

2 (4.4)

G163 Wa

3 (6.6)

Minor INI accessory mutations

 V201I

37 (82.2)

 I203 M

6 (13.3)

  1. aUnusual mutations in non-polymorphic sites associated with minor INI mutations (according to The Stanford University HIV drug resistance database; http://hivdb.stanford.edu)