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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Human papillomavirus 16-specific cell-mediated immunity in children born to mothers with incident cervical intraepithelial neoplasia (CIN) and to those constantly HPV negative

Fig. 2

HPV16 E2, E6, and E7-specific cytokine secretion in case and control groups. Secreted cytokines were determined only from PBMCs showing proliferative response against HPV16 peptides (LST+). The box is bounded on the top by the third quartile, the bottom by the first quartile, and divided by the median. The minimum and maximum are indicated by the whiskers. If three or fewer values are detected the median and/or min and max values are connected with vertical line. The concentrations of TNF-α showed statistically significant difference between groups *p = 0.031, **p = 0.039

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