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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Reversion of malignant phenotypes of human glioblastoma cells by β-elemene through β-catenin-mediated regulation of stemness-, differentiation- and epithelial-to-mesenchymal transition-related molecules

Fig. 6

β-Elemene impaired the invasiveness of glioblastoma cells by reducing the expression of β-catenin. a Glioblastoma cells were separated into the following three groups: DMSO, 50 µg/ml β-elemene + DMSO, and 50 µg/ml β-elemene + 10 µM XAV939 (dissolved in DMSO) for 12 h. Transwell assays were performed to determine the invasiveness of the cells. b The results of (a) are illustrated graphically. c The molecular structure of XAV939. The results are representative of three independent experiments, and the values are presented as the mean ± SD (*p < 0.05, **p < 0.01)

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