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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivo

Fig. 2

miR-214 inhibits XBP1 expression and is upregulated in hypertrophic and failing heart. a Western blots of ATF6 and IRE1 in rat heart after AAC. b Western blots of XBP1 s in untreated and miR-214-treated H9C2 (2-1) cells. c Real-time PCR analysis of miR-214 in rat heart after AAC treatment. n = 6. d Real-time PCR analysis of miR-214 in rat heart after ISO infusion. Values are mean ± SEM. n = 6. *P < 0.05 compared with control

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