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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivo

Fig. 1

Cardiac XBP1 expression is upregulated in hypertrophic and failing heart. a Left ventricular weight/body weight (LVW/BW, grams) after AAC. b Cross-sectional area (CSA) of cardiomyocytes after AAC. c, d Hemodynamic analysis of rats at 1, 4 and 8 weeks of AAC: (Upper) dP/dtmax (mmHg/s) and (lower) dP/dtmin (mmHg/s). e Western blots of Grp78, XBP-1 s, and ANP in rat heart after AAC. f Western blots of Grp78, XBP-1 s, and ANP in ISO-treated heart samples. n = 6 for a, c, d; n = 3 for b. *P < 0.05 compared with control

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