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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Granulocyte transfusions in children and adults with hematological malignancies: benefits and controversies

Fig. 2

Abundance of selected transcripts in leukocytes from donors receiving G-CSF and dexamethasone. This dataset was selected among studies currently available in NCBI’s Gene Expression Omnibus (GEO; http//www.ncbi.nlm.nih.gov/sites/GDSbrowser?acc=GSE12841). Granulocytes were isolated from three individuals before and 18 h after treatment with G-CSF and dexamethasone. Some of the control cells were cultured overnight in HBSS medium with or without the addition of G-CSF and dexamethasone. Total RNA from each experimental condition was compared to pooled RNA of control granulocytes. The genome-wide pattern of gene expression was analyzed with DNA microarrays (Agilent-012391 Whole Human Genome Oligo Microarray G4112A) [23]. Data were compared with the Mann–Whitney U test. A p value <0.05 was considered to denote statistical significance

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