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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: HALT & REVERSE: Hsf1 activators lower cardiomyocyt damage; towards a novel approach to REVERSE atrial fibrillation

Fig. 1

Proteostasis is the balance between protein expression, folding, function and clearance in the cell. When proteins are generated at the ribosomes after translation, chaperones, such as heat shock proteins, guide proper protein folding, and when not folded correctly, they guide remodeling of the protein. Furthermore, these chaperones have a role in limiting protein aggregation and they have a role in protein degradation

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