Table 3 Rheumatoid factor (RF) ELISA analysis of ADA-positive IFX-treated patients and ADA-negative untreated healthy control sera
From: B cell epitopes on infliximab identified by oligopeptide microarray with unprocessed patient sera
Patient ID | RF (U/ml) | Control ID | RF (U/ml) | ||||
|---|---|---|---|---|---|---|---|
IgM | IgA | IgG | IgM | IgA | IgG | ||
438 | 1.1 | 1.4 | 30.7 | P* | 2.0 | 3.4 | 8.4 |
452 | 5.1 | 2.8 | 5.0 | F10 | 3.5 | 6.5 | 15.0 |
485 | 1.4 | 1.8 | 6.2 | F22 | 1.9 | 2.3 | 14.2 |
522 | 1.7 | 3.2 | 16.4 | F28 | nd | nd | nd |
587 | 3.3 | 2.0 | 3.6 | F31 | 2.3 | 1.8 | 7.2 |
609 | 3.8 | 9.1 | 18.3 | F32 | 3.1 | 18.9 | 5.7 |
623 | 3.1 | 8.1 | 10.2 | F33 | 3.9 | 3.4 | 7.4 |
626 | 2.9 | 8.2 | 9.4 | F34 | 1.3 | 2.4 | 8.4 |
638 | 2.7 | 2.8 | 4.7 | F38 | 2.8 | 5.2 | 10.3 |
639 | 2.7 | 2.3 | 5.0 | F41 | 2.2 | 2.0 | 10.3 |
648 | 2.3 | 11.4 | 27.5 | F42 | 1.5 | 3.2 | 13.1 |
652 | 1.9 | 7.8 | 12.3 | F44 | 3.5 | 28.3 | 11.3 |
660 | 2.2 | 3.4 | 12.3 | F45 | 0.9 | 0.2 | 3.4 |
681 | 1.3 | 12.2 | 8.7 | F46 | 2.2 | 3.5 | 24.4 |
694 | 2.9 | 3.3 | 10.2 | F47 | nd | nd | nd |
695 | 2.9 | 4.0 | 14.5 | ||||
719 | 1.1 | 8.8 | 7.4 | ||||
721 | 2.7 | 0.9 | 4.1 | ||||
722 | 4.4 | 4.5 | 3.3 | ||||
724 | 0.9 | 21 | 4.8 | ||||