Table 4 Cox proportional hazard regression model analysis
Variables | Univariate Cox’s regression analysis | Multivariate Cox’s regression analysis | ||||
|---|---|---|---|---|---|---|
Relative risk | 95Â % CI | P value | Relative risk | 95Â % CI | P value | |
Differentiation | ||||||
 Moderate-well versus poor | 0.397 | 0.244–0.646 | <0.001 |  |  |  |
Lymphovascular invasion | ||||||
 Present versus absent | 3.606 | 2.310–5.627 | <0.001 | 1.611 | 1.013–2.561 | 0.044 |
CD147 expression | ||||||
 Positive versus negative | 2.364 | 1.422–3.931 | 0.001 | 2.023 | 1.193–3.430 | 0.009 |
MMP-11 expression | ||||||
 Positive versus negative | 2.281 | 1.206–4.316 | 0.011 | 2.094 | 1.083–4.047 | 0.028 |
T stage | ||||||
 T1 + T2 versus T3 + T4 | 4.432 | 1.619–12.132 | 0.004 |  |  |  |
N stage | ||||||
 N0 versus N1 + N2 + N3 | 6.616 | 3.486–12.556 | <0.001 |  |  |  |
Metastasis | ||||||
 No versus yes | 32.746 | 12.946–82.860 | <0.001 | 25.970 | 10.001–67.442 | <0.001 |