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Table 3 Association of CD147 and MMP-11 expression with clinicopathological features

From: Expression of CD147 and matrix metalloproteinase-11 in colorectal cancer and their relationship to clinicopathological features

Clinicopathological features

CD147 expression

MMP-11 expression

Positive (%)

Negative (%)

P value

Positive (%)

Negative (%)

P value

Gender

 Male

83 (64.34)

46 (35.66)

0.377

99 (76.74)

30 (23.26)

0.892

 Female

52 (58.43)

37 (41.57)

69 (77.53)

20 (22.47)

Age (years)

 <60

57 (57.58)

42 (42.42)

0.228

77 (77.78)

22 (22.22)

0.819

 ≥60

78 (65.53)

41 (34.45)

91 (76.47)

28 (23.53)

Differentiation

 Poor

26 (66.67)

13 (33.33)

0.501

32 (82.05)

7 (17.95)

0.414

 Moderate-well

109 (60.89)

70 (39.11)

136 (75.98)

43 (24.02)

Size

 <4 cm

62 (59.62)

42 (40.38)

0.502

81 (77.88)

23 (22.12)

0.783

 ≥4 cm

73 (64.04)

41 (35.96)

87 (76.32)

27 (23.68)

Lymphovascular invasion

 Absent

93 (62.42)

56 (37.58)

0.827

110 (73.83)

39 (26.17)

0.095

 Present

42 (60.87)

27 (39.13)

 

58 (84.06)

11 (15.94)

 

Depth of invasion

 T1/T2

16 (48.48)

17 (51.52)

0.084

22 (66.67)

11 (33.33)

0.123

 T3/T4

119 (64.32)

66 (35.68)

146 (78.92)

39 (21.08)

Lymph node metastasis

 N0

47 (52.81)

42 (47.19)

0.021

62 (69.66)

27 (30.34)

0.031

 N1–2

88 (68.22)

41 (31.78)

106 (82.18)

23 (17.83)

Distant metastasis

 M0

53 (63.86)

30 (36.14)

<0.001

74 (69.81)

32 (30.19)

0.013

 M1

53 (39.26)

82 (60.74)

94 (83.93)

18 (16.07)

TNM stage

 I + II

37 (49.33)

38 (50.67)

0.006

52 (69.33)

23 (30.67)

0.049

 III + IV

98 (68.53)

45 (31.47)

116 (81.11)

27 (18.89)