Fig. 2

Representative immunohistochemical staining of CD147 and MMP-11 in CRC tissue and matched normal mucosa. a, b show CD147 staining in normal mucosa and CRC tissue, respectively (magnification ×100). c, d show MMP-11 staining in normal mucosa and CRC tissue, respectively (magnification ×100). As is shown, CD147 protein is predominantly localized on cell membrane and in the cytoplasm, while MMP-11 protein was of cytoplasmic staining