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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway

Fig. 5

CHBP blocked PI3 K/Akt/FoxO3a signaling. a Western blotting analysis of the PI3K/Akt/FoxO3a pathway. Quantitative results for b PI3K p85, c p-Akt Ser473, d p-Akt Th308, e E-cadherin, f α-SMA, g vimentin, h p-FoxO3a Ser253, and i p-FoxO3a Ser318/321 presented as the mean ± SD of the optical density of each band (n = 6). δ p < 0.05, δδ p < 0.01, δδδ p < 0.001 compared with the TGF-β group. *p < 0.05, **p < 0.01, ***p < 0.001 compared with the TGF-β + CHBP group. # p < 0.05, ## p < 0.01, ### p < 0.001 compared with the TGF-β + CHBP + control siRNA group

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