Journal of Translational Medicine

Table 2 Correlation of IBC and DCIS expression of ER, PR, and HER2 in mutation carriers with IBC with concurrent DCIS, stratified by BRCA mutation

From: DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3

IBC ER intensity	BRCA1					BRCA2
	DCIS ER intensity					DCIS ER intensity
	0	1	2	3	P value*	0	1	2	3	P value*
0	23	0	2	1	<0.001	4	1	0	0	<0.001
1	1	0	0	0		0	0	0	0
2	0	0	1	3		0	0	4	3
3	0	0	0	2		0	0	1	8

IBC PR intensity	DCIS PR intensity					DCIS PR intensity
IBC PR intensity	0	1	2	3	P value*	0	1	2	3	P value*
0	23	0	3	2	<0.001	5	0	0	0	0.003
1	0	0	0	0		0	0	1	1
2	0	0	0	1		0	0	2	2
3	0	0	0	4		0	1	1	1

IBC HER2 intensity	DCIS HER2 intensity					DCIS HER2 intensity
IBC HER2 intensity	0	1	2	3	P value*	0	1	2	3	P value*
	16	5	0	0	0.46	7	5	0	0	<0.001
	6	4	0	0		1	6	0	0
	2	1	0	0		0	1	0	0
	0	0	0	0		0	0	0	2

* Linear trend test for a table with ordered rows and columns

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ISSN: 1479-5876

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