Inclusion criteria |
---|
Age between 18 and 70 years |
CLI (TASC 2) |
None surgical nor endovascular option |
Written informed consent |
Exclusion criteria |
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Clinical instability |
Extensive gangrene (proximal to forefoot) |
All serious systemic disease |
Life expectancy <24 months |
Child bearing age |
Allergy |
Previous similar studies |
Previous experimental drug studies within 3 months |
Conflict of interest with the study |