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Table 2 Neutralizing activity of anti-cytokine autoantibodies in HZ and PHN

From: Anti-cytokine autoantibodies in postherpetic neuralgia

Cytokine

Pt. ID

Group

Ab level (LU)a

Other samplesa (95 % CI)

Neutralizing activityb

IFN-α

56

PHN

1,465,000

1388 ± 89 (LU)

Neutralizing

IFN-α

6

HZ

335,000

1388 ± 89 (LU)

Partially neutralizing

IFN-γ

123

PHN

125,000

2943 ± 535 (LU)

Not neutralizing

IFN-γ

207

PHN

541,000

2943 ± 535 (LU)

Partially neutralizing

IFN-γ

322

PHN

939,000

2943 ± 535 (LU)

Not neutralizing

IL-6

226

PHN

2,371,000

1555 ± 419 (LU)

Neutralizing

GM-CSF

205

PHN

575,000

2079 ± 252 (LU)

Neutralizing

GM-CSF

215

HZ

145,000

2079 ± 252 (LU)

Not neutralizing

  1. aAntibody levels determined by LIPS
  2. bCytokine neutralization activity as described in the methods