Fig. 7From: Wnt signaling in age-related macular degeneration: human macular tissue and mouse modelRetinal A2E accumulation in the Ccl2 −/− /Cx3cr1 −/− /rd8 mice. Retinal A2E levels in anti-LRP6 treated and control eyes of Ccl2 −/− /Cx3cr1 −/− /rd8. A2E concentrations were determined by HPLC in the retina. The A2E level was reduced after anti-LRP6 antibody injection. n = 5 from each group; *: p < 0.05Back to article page