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Table 1 Plasma lipids levels in apoE−/− mice

From: PEP-1-MsrA ameliorates inflammation and reduces atherosclerosis in apolipoprotein E deficient mice

 

Time (weeks)

Control

MsrA

PEP-1-MsrA

TC (mg/dL)

0

522.9 ± 89.1

561.6 ± 76.6

528.0 ± 28.1

 

4

696.7 ± 116.9

727.1 ± 92.8

699.7 ± 83.7

 

8

824.6 ± 67.5

809.1 ± 126.9

863.8 ± 143.1

 

12

888.6 ± 75.7

929.9 ± 91.7

867.3 ± 119.1

TG (mg/dL)

0

127.4 ± 19.7

139.3 ± 25.4

137.7 ± 21.3

 

4

170.4 ± 20.7

164.9 ± 22.0

168.3 ± 16.1

 

8

188.0 ± 30.7

206.2 ± 40.4

192.6 ± 35.7

 

12

191.5 ± 41.5

185.3 ± 30.0

194.3 ± 30.6

  1. Data are given as the mean ± SEM, n = 10. The statistical analysis was performed using a two-tailed Student’s t test. Mice were fed a Western-type diet and intraperitoneally injected with PBS, MsrA or PEP-1-MsrA proteins for 12 weeks
  2. TC total cholesterol, TG triglycerides