Circulating microRNAs as biomarkers for diffuse myocardial fibrosis in patients with hypertrophic cardiomyopathy

Table 4 AUC for individual miRNA

	AUC	P value	Cutoff	Sensitivity (%)	Specificity (%)
miR-18a-5p	0.742	0.002	6.65	70.4	71.4
miR-146a-5p	0.737	0.003	50.04	69.6	78.6
miR-30d-5p	0.729	0.004	15.19	65.2	84.4
miR-17-5p	0.722	0.005	0.16	60.9	71.9
miR-200a-3p	0.721	0.005	0.085	60.9	75
miR-19b-3p	0.712	0.007	127.38	59.3	78.6
miR-21-5p	0.710	0.007	37.18	59.3	82.1
miR-193-5p	0.709	0.008	0.11	59.3	82.1
miR-10b-5p	0.701	0.010	0.05	60.9	75
miR-15a-5p	0.694	0.013	2.88	59.3	71.4
miR-192-5p	0.681	0.021	0.72	63	75
miR-296-5p	0.681	0.021	0.26	56.5	71.4
miR-29a-3p	0.717	0.006	9.31	63	82.1
miR-133a-3p	0.663	0.038	1.42	63	78.6

Receiver operating characteristic (ROC) curve analysis was used to calculate the area under the curve (AUC) of individual miRNA for diagnosing diffuse fibrosis

ISSN: 1479-5876