| T1 ≥ 470 | T1 < 470 |
---|---|---|
n | 28 | 27 |
Gender (m/f) | 22/6 | 22/5 |
Age (years) | 49.1 ± 14.0 | 49.9 ± 10.8 |
Height (cm) | 171.3 ± 10.7 | 174.9 ± 7.9 |
Weight (kg) | 81.8 ± 18.7 | 88.5 ± 14.7 |
Body mass index (kg/m2) | 27.6 ± 4.5 | 28.9 ± 4.0 |
Family history of HCM (%) | 35.7Â % | 11.1Â %* |
Resting heart beat (beats/min) | 63.9 ± 10.5 | 61.5 ± 16.1 |
Systolic blood pressure (mmHg) | 129.7 ± 17.3 | 130.8 ± 14.9 |
Diastolic blood pressure (mmHg) | 75.0 ± 9.1 | 71.6 ± 8.6 |
eGFR (mL/min/1.75 m2) | 83.9 ± 7.6 | 79.7 ± 13.8 |
Medications | ||
 β-blockers | 50 % | 63 % |
 Calcium channel blockers | 14.3 % | 29.6 % |
 Angiotensin convert enzyme inhibitor | 10.7 % | 22.2 % |
 Angiotensin receptor blockers | 21.4 % | 3.7 % |
Echocardiography | ||
 Left atrial volume indexed, ml/m2 | 48.4 ± 18.2 | 49.6 ± 13.9 |
 E/A ratio | 1.35 ± 0.63 | 1.40 ± 0.67 |
 Deceleration time (ms) | 200.0 ± 64.0 | 226.4 ± 44.0 |
 Septal e′ (cm/s) | 6.5 ± 1.5 | 5.9 ± 1.7 |
 Lateral e′ (cm/s) | 8.5 ± 1.9 | 7.6 ± 2.9 |
 Mean e′ (cm/s) | 7.5 ± 1.4 | 6.7 ± 2.1 |
 Septal E/e′ | 12.5 ± 3.8 | 14.8 ± 5.9 |
 Lateral E/e′ | 9.8 ± 3.8 | 12.0 ± 5.1 |
 Mean E/e′ | 11.0 ± 3.4 | 13.4 ± 5.1 |
 Resting LVOT gradient (mmHg) | 32.8 ± 39.6 | 49.9 ± 51.0 |
CMR | ||
 T1 times (ms), excluding LGE | 536.3 ± 54.6 | 441.0 ± 30.0*** |
 T1 times (ms), including LGE | 521.3 ± 66.4 | 432.3 ± 26.2*** |
 T1 times (ms, corrected values) | 518.7 ± 55.2 | 423.8 ± 34.1*** |
 Blood T1 times (ms) | 310.7 ± 30.4 | 296.0 ± 29.3 |
 Septal thickness (mm) | 20.3 ± 5.8 | 19.1 ± 3.3 |
 Lateral wall thickness (mm) | 8.6 ± 1.8 | 9.2 ± 1.9 |
 Septal/lateral wall thickness | 2.4 ± 0.7 | 2.1 ± 0.5 |
 LV mass index (g/BSA) | 92.6 ± 35.0 | 87.4 ± 22.4 |
 LV ejection fraction (%) | 68.5 ± 7.3 | 70.8 ± 6.5 |
 Presence of LGE (%) | 85.7 % | 81.5 % |
 Quantity of LGE (% of LV) mass | 5.6 ± 7.5 | 4.7 ± 6.1 |