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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

Fig. 5

Examples of progressed atherosclerotic lesions in left anterior descending artery (LAD) and abdominal aorta. Movat’s pentachrome staining. Scale bar 500 µm. a LAD, high-fat/high-cholesterol fed animal (HFD), pathological intimal thickening. Inset cholesterol clefts and calcification. b LAD, HFD, fibroatheroma with marked calcification. Inset cap of the lesion. c Pathological intimal thickening in aorta. Inset area of calcification. d Fibroatheroma in aorta. Inset cholesterol clefts disrupted internal elastic lamina and angiogenesis

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Journal of Translational Medicine

ISSN: 1479-5876

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