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Table 2 Numbers of serum peptidome components with abundances different between compared groups of individuals

From: Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study

Groups/differences

Control vs. cancer (all cases)

Locally advanced vs. metastatic cancer

Local/no spread vs. metastatic cancer

Local/spread vs. metastatic cancer

Local/no spread vs. local/spread cancer

n

50 vs. 53

35 vs. 18

19 vs. 18

16 vs. 18

19 vs. 16

p < 0.05

182

88

74

75

11

FDR

7 %

14 %

17 %

17 %

100 %

p < 0.05/Bonferroni

101

23

11

16

0

AUC (SVM)

0.94

0.91

0.92

0.97

0.48

  1. Shown are numbers of differentiating components that reached threshold of statistical significance p = 0.05 (with corresponding FDR estimation) or threshold strengthened with the Bonferroni correction, and power of SVM classifier built of peptidome components (characterized by the AUC value)