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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: PIWIL2 promotes progression of non-small cell lung cancer by inducing CDK2 and Cyclin A expression

Fig. 5

PIWIL2 promotes tumor growth, and CDK2 and Cyclin A expression in nude mice. a Injection with A549 cells containing the PIWIL2 over-expression vectors promoted tumor growth in a nude mice model (n = 5). Real-time PCR (b), western blot (c) and IHC (d) analysis indicated that over-expression of PIWIL2 increased CDK2 and Cyclin A expression in tumor tissues. Asterisk indicates the significant difference between the groups (P < 0.05). For IHC, scale bars = 100 μm

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