From: Metabolomic approach to profile functional and metabolic changes in heart failure
Class | Variables | VIP | Coefficient values | Metabolites | ||
---|---|---|---|---|---|---|
Group A | Group B | Group C | ||||
Group A | 1.94 | 2.46 | 0.14 | −0.07 | −0.06 | Acetate |
0.9 | 2.40 | 0.07 | 0.05 | −0.11 | 2-Hydroxybutyrate | |
0.98 | 2.27 | 0.11 | −0.02 | −0.08 | Leucine/isoleucine | |
0.94 | 1.92 | 0.08 | −0.01 | −0.07 | Leucine/isoleucine | |
1.66 | 1.88 | 0.05 | 0.03 | −0.08 | 2-Hydroxybutyrate/leucine | |
1.18 | 1.67 | 0.09 | −0.04 | −0.04 | 3-Hydroxybutirate/ fucose | |
1.46 | 1.52 | 0.06 | −0.01 | −0.05 | Alanine/isoleucine | |
1.5 | 1.44 | 0.04 | 0.03 | −0.06 | Alanine/isoleucine | |
2.42 | 1.26 | 0.06 | −0.06 | 0.01 | 3-Hydroxybutirate/glutamina | |
1.1 | 1.22 | 0.05 | 0.01 | −0.05 | 3-Methyl-2-oxovalerate | |
1.7 | 1.20 | 0.04 | −0.05 | 0.01 | 2-Hydroxybutyrate | |
1.22 | 1.18 | 0.04 | −0.05 | 0.01 | 3-Hydroxybutirate/ fucose | |
Group B | 3.38 | 3.45 | −0.22 | 0.13 | 0.08 | Proline/methanol |
3.9 | 2.12 | −0.08 | 0.07 | 0.01 | Glucose | |
3.22 | 1.78 | −0.05 | 0.11 | −0.06 | Glycero-3-phosphocholine | |
3.94 | 1.76 | −0.06 | 0.07 | −0.01 | Glucose/creatine | |
1.9 | 1.71 | −0.07 | 0.11 | −0.04 | 4-Aminobutyrate | |
3.42 | 1.54 | 0.03 | 0.08 | −0.10 | Glucose | |
3.74 | 1.45 | −0.01 | 0.01 | 0.00 | Glucose | |
1.26 | 1.44 | −0.04 | 0.09 | −0.05 | Methylmalonate | |
1.86 | 1.25 | −0.01 | 0.06 | −0.05 | 4-Aminobutyrate | |
2.34 | 1.17 | −0.03 | 0.07 | −0.04 | 3-Hydroxybutirate/glutamate | |
3.98 | 1.07 | −0.08 | 0.04 | 0.04 | 2-Hydroxybutyrate | |
2.7 | 1.01 | −0.07 | 0.05 | 0.02 | Citrate | |
1.34 | 4.43 | 0.00 | −0.23 | 0.22 | Lactate | |
3.7 | 3.05 | −0.15 | 0.01 | 0.12 | Glucose | |
Group C | 3.66 | 2.52 | −0.12 | −0.02 | 0.13 | Glucose/glycero-3-phosphocholine |
3.62 | 2.50 | −0.11 | −0.03 | 0.13 | Myo-inositol/glycero-3-phosphocholine | |
3.58 | 2.40 | −0.07 | −0.05 | 0.11 | Myo-inositol/glycine | |
3.82 | 1.94 | −0.03 | −0.06 | 0.08 | Glucose/guanidoacetate | |
4.14 | 1.65 | 0.00 | −0.09 | 0.08 | Lactate | |
3.3 | 1.51 | −0.03 | −0.05 | 0.07 | Myo-inositol/glycine/OTMA | |
4.02 | 1.48 | −0.08 | 0.01 | 0.06 | 2-Hydroxybutyrate | |
2.06 | 1.36 | −0.06 | −0.04 | 0.10 | N-acetyl groups | |
4.06 | 1.09 | −0.05 | −0.01 | 0.05 | Myo-inositol/creatinine | |
3.14 | 1.02 | −0.08 | 0.03 | 0.04 | Methylmalonate |