Fig. 3

APT imaging of brain tumor (glioblastoma multiforme) in a human patient. Anatomical T2 weighted (a) and post contrast T1 weighted (b) images are showing diffuse tumor in parietal lobe. APT weighted image (c) shows high contrast in tumor than normal brain parenchyma. Immunohistochemical staining of Ki-67 (d) shows very high proliferative activity in tumor with high cellular density. Reproduced with permission from the Oxford University Press and Togao et al. [83]