The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study

Table 1 Characteristics of selected polymorphisms

HGN	Gene name	dbSNP^a	Tag-SNP^b	Chr position	Reference^c	MAF^d
CAT	Catalase	rs1049982	Y	11:34417117	c.-20C > T	0.36
SOD3	Superoxidedismutase 3	rs2536512	Y	4:24410413	c.172G > A (p.A58T)	0.37
GPX1	Glutathione peroxidase 1	rs3448	Y	3:49371755	c.*891C > T	0.25
TXN	Thioredoxin	rs4135168	Y	9:112056706	c.24 + 1807G > A	0.12
		rs2301241	Y	9:112059329	c.-793T > C	0.48
XDH	Xanthine dehydrogenase	rs17323225		2:31446769	c.1936T > C (p.I646V)	0.06
COMT	Catechol-O-methyltransferase	rs740603	Y	22:19945177	c.-91-3545G > A	0.39

HGN HUGO gene nomenclature, Chr chromosome
^aNCBI dbSNP Build 126
^bTag-SNP by HapMap in Caucasoid subjects (Y yes)
^cBegins in the first nucleotide 5′ of the ATG start codon, Build 126, Ensembl release 41 as suggested by the Human Gene Nomenclature Committee (HGNC)
^dMAF (minor allele frequency), data obtained from 1000 genomes

ISSN: 1479-5876