Fig. 6

Inhibition of miR-195 partially reversed the over-expression of miR-195 induced effect. a Inhibitor of miR-195 suppressed the expression of miR-195. DU145 and PC3 cells were co-transfected with miR-195-Inhi (vs. Inhi-NC) and miR-195 (vs. NC). The expression of miR-195 was determined by real-time PCR, snRNA U6 served as an internal control (*P < 0.05). b The expression of Fra-1 was determined by western blot analysis after miR-195 inhibitor treatment, western-blot results should be analyzed quantitatively (*P < 0.05). c The prostate cancer cells migration and invasion ability was restored after miR-195-Inhi transfection (×100) (*P < 0.05)