Table 2 Cox regression analysis of survival—univariate analysis of single factors
From: Loss of tapasin correlates with diminished CD8+ T-cell immunity and prognosis in colorectal cancer
HR | 95 % CI | P-value | ||
|---|---|---|---|---|
Tapasin | Baseline | 1.00 | ||
By intensity | 0.60 | 0.42–0.85 | 0.004 | |
pT | pT1-2 | 1.00 | ||
pT3-4 | 2.74 | 1.31–5.73 | 0.007 | |
pN | pN0 | 1.00 | ||
pN1-2 | 4.14 | 2.39–7.18 | <0.001 | |
pM | pM0 | 1.00 | ||
pM1 | 6.08 | 3.38–10.92 | <0.001 | |
Adjuvant therapy | None | 1.00 | ||
Tx | 1.48 | 0.89–2.48 | 0.143 | |
Intratumoral CD8+ CTL | Low | 1.00 | ||
High | 0.28 | 0.13–0.60 | 0.001 |