Pt | Age (year) | Sex | Duration (year) | Location/severity | Medication before step-up FMT | FMT strategy | Clinical response to FMT | Medication after step-up FMT | Free of steroid | |
---|---|---|---|---|---|---|---|---|---|---|
Status of steroids usage (equivalent to prednisone, mg/day) | Combination therapy | |||||||||
1 | 11 | M | 1 | Left sided/S3 | Maintenance dose 10 mg/day | Mesalamine 3.0 g/day | One FMT | No response | Prednisone 10 mg/day as maintenance and then switch to anti-TNF therapy for half a year | No |
2 | 48 | F | 1 | Extensive/S3 | Relapse after withdrawal of prednisone to 10 mg/day | AZA 50 mg/day | One FMT | Short-term improvement and flared within 1 month | Prednisone 15 mg/day as maintenance | No |
3 | 47 | M | 9 | Extensive/S3 | Relapse after withdrawal of prednisone | AZA 50 mg/day | One FMT | Short-term improvement and flared within 1 month | Prednisone 10 mg/day as maintenance | No |
4 | 19 | F | 4 | Extensive/S3 | Maintenance dose 10 mg/day | Mesalamine 3.0 g/day | One FMT | No response | Switch to anti-TNF at the first week | No |
5 | 20 | F | 6 | Extensive/S3 | Maintenance dose 20 mg/day for 3 years before FMT | Mesalamine 3.0 g/day | One FMT | Short-term improvement and flared within 1 month | Prednisone 20 mg/day as maintenance | No |
6 | 32 | M | 1 | Extensive/S3 | Maintenance dose 10 mg/day | Mesalamine 4.0 g/day | One FMT | S3 to S1 | Mesalamine 3.0 g/day as for 4 months | Yes |
7 | 32 | M | 8 | Extensive/S3 | Serious flare with shock and diarrhea after withdrawal of prednisone to 20 mg/day | Mesalamine 4.0 g/day | Two FMTs | S3 to S2 | Scheduled prednisone and then switch to Mesalamine 3.0 g/day for 4 months | Yes |
8 | 34 | M | 4 | Extensive/S3 | Relapse immediately after withdrawal of prednisone | TCM | One FMT | S3 to S2 | Mesalamine 3.0 g/day for 5 months | Yes |
9 | 23 | M | 2 | Extensive/S3 | Maintenance dose 10 mg/day for 7 months | Mesalamine 4.0 g/day | Two FMTs | S3 to S2 | Mesalamine 3.0 g/day for 6 months | Yes |
10 | 38 | M | 8 | Extensive/S3 | Maintenance dose 10 mg/day for more than 2 years | AZA 50 mg/day | One FMT | S3 to S0 | Mesalamine 3.0 g/day for 9 months | Yes |
11 | 39 | M | 7 | Left sided/S2 | Relapse immediately after withdraw of prednisone to 15 mg/day | – | One FMT | S2 to S0 | Mesalamine 3.0 g/day for 18 months | Yes |
12 | 37 | F | 3 | Proctitis/S2 | Maintenance dose 35 mg/day for 31 months | Mesalamine 4.0 g/day | One FMT | S2 to S0 | Mesalamine 3.0 g/day for 11 months | Yes |
13 | 35 | M | 1 | Extensive/S3 | Maintenance dose 20 mg/day for 3 years and 2 months | Mesalamine 4.0 g/day | Two FMTs | S3 to S0 | Follow by scheduled prednisones and then switch to Mesalamine 3.0 g/day as maintenance without relapse for 12 months | Yes |
14 | 27 | M | 2 | Extensive/S3 | Relapse after withdrawal of prednisone to 15 mg/day | – | Two FMTs | Short-term improvement but flared soon afterward. Long-term remission of multiple skin infections | Prednisone 15 mg/day as maintenance | No |
15 | 33 | M | 6 | Left sided/S3 | Maintenance dose 10 mg/day for 2 years | – | One FMT | S3 to S2, but lost to follow-up | – | – |