Table 4 Zonal measurement of cartilage thickness and measurement and scoring of the osteophytes on histology slides (safranin O) at the medial tibial plateau
Parameter | Unit | Area | SHAM | MMT |
|---|---|---|---|---|
Cartilage thickness | μm | z1 | 536.15 ± 18.78 | 1035.51 ± 34.62** |
z2 | 916.96 ± 21.14 | 182.76 ± 20.05** | ||
z3 | 1092.5 ± 23.13 | 1016.00 ± 25.81 | ||
Damage score (1–5) | score | z1–z3 | 0.2 ± 0.04 | 4.3 ± 1.62** |
Cartilage matrix loss width | μm | 0 % | 307.44 ± 145.73 | 4586.24 ± 846.11** |
50 % | 126.53 ± 82.22 | 2631.76 ± 350.87** | ||
100 % | 46.36 ± 145.73 | 1843.15 ± 304.20** | ||
Total cartilage degeneration width | μm | z1–z3 | 312.46 ± 35.26 | 4965.55 ± 930.87** |
Significant cartilage degeneration width | μm | z1–z3 | 6.32 ± 10.50 | 1987.53 ± 962.81** |
Osteophyte size | μm | z1 | 26.42 ± 15.81 | 480.19 ± 62.33** (large) |