Skip to main content

Table 2 The results of different gut microbial intervention methods

From: Gut microbiota and allogeneic transplantation

 

Intervention methods

Results

Animal/human study

LT

SDD [81–85]

Reducing the high incidence of infection [81]

Human study

Gram-positive microorganisms infection predominated over Gram-negative rods and anaerobes [82]

Human study

No infection prevention [83–85]

Human study

Antibiotics [57]

Partly ameliorating enhanced ischemia/reperfusion injury

Animal study

LAB and fibers [87]

Reducing bacterial infection rates

Human study

Only fibers [87]

Reducing incidence of severe infections

Human study

Probiobics [88, 89]

Promoting partial restoration of intestinal microflora and improving intestinal barrier function [88]

Animal study

Reducing the liver injury by acute rejection [89]

Animal study

SBT

Probiotics [90]

Ameliorating small bowel histological injuries and reducing BT

Animal study

HSCT

TGID [86]

Preventing acute GVHD

Human study

Polymyxin B [70]

Ameliorating GVHD

Animal study

Probiotics [91]

Reduceing acute GVHD and improving survival

Animal study

  1. LT liver transplantation, SBT small bowel transplantation, HSCT hematopoietic stem cell transplantation, KT kidney transplantation, LAB actic acid bacteria, SDD selective digestive decontamination and TGID total gastro-intestinal decontamination