Foxp3-modified bone marrow mesenchymal stem cells promotes liver allograft tolerance through the generation of regulatory T cells in rats

Table 1 Experimental groups and liver allograft survival in ACI recipients

Group	n	Injected cells	Graft survival (days)	MST (days)
1	6	No	11, 13 × 2, 14, 15, 16	13.5
2	8	Lewis MSC	16, 18, 20, 21 × 3, 24, 26	21.0*
3	8	Lewis Foxp3-MSC	63, >100 × 7	100*^,†
4	6	Lewis FUGW-MSC	18 × 2, 20 × 2, 21, 23	20.0*
5	6	Lewis Foxp3-MSC + α-CD25	12, 14 × 3, 16, 18	14.0
6	6	Lewis Foxp3-MSC + IgG	>100 × 6	100*^,†
7	6	BN Foxp3-MSC	17, 19, 25, 26, 30, 35	25.5*
8	6	ACI Foxp3-MSC	31, 35, 41, 73, >100 × 2	57.0*^,†,††

* p < 0.05 vs untreated group; ^† p < 0.05 vs MSC group; ^†† p < 0.05 vs Foxp3-MSC group

ISSN: 1479-5876