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Table 3 Maximum toxicity per patient

From: Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer

Toxicity Cohort 1 (n = 5) Cohort 2 (n = 4) Cohort 3 (n = 3) All cohort (n = 12)
Grade Grade Grade Grade
1–2 3 1–2 3 1–2 3 1–2 3
Hematological
 Neutropenia 0 0 1 0 0 1 1 1
 Lymphopenia 3 1 3 0 0 0 6 1
 Anemia 3 1 3 1 2 0 8 2
 Thrombocytopenia 2 1 1 0 0 0 3 1
 Elevated AST 2 0 1 0 0 0 3 0
 Elevated ALT 0 0 1 0 0 0 1 0
 Elevated total billirubin 0 1 2 0 1 0 3 1
Non-hematological
 Fatigue 2 0 3 0 3 0 8 0
 Fever 1 0 0 0 0 0 1 0
 Anorexia 0 1 0 1 0 0 0 2
 Nausea 0 0 0 0 2 0 2 0
 Diarrhea 0 0 2 0 0 0 2 0
 Constipation 1 0 2 0 0 0 3 0