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Table 2 Platelet reactivity and activity of female and male stroke sufferers

From: Platelets, gender and acute cerebral infarction

 

Females (mean ± SD) (n = 31)

Males (mean ± SD) (n = 42)

p value

Platelet counts (×109/L)

295 ± 105

245 ± 58

0.013

Platelet distribution width (%)

15.7 ± 1.7

16.4 ± 0.9

0.03

Platelet-bound fibrinogen after agonist provocation

 ADP (1.7 μmol/L) (%)

23 ± 16

32 ± 17

0.038

 ADP (8.5 μmol/L) (%)

54 ± 21

62 ± 19

NS

 TRAP-6 (57 μmol/L) (%)

35 ± 23

52 ± 29

0.016

 TRAP-6 (74 μmol/L) (%)

51 ± 24

63 ± 22

NS

Platelet-bound P-selectin after agonist provocation

 TRAP-6 (57 μmol/L) (%)

20 ± 13

15 ± 7

NS

 TRAP-6 (74 μmol/L) (%)

41 ± 22

44 ± 18

NS

Platelet-bound P-selectin

 Without agonist (%)

4 ± 2

4 ± 1

NS

Soluble P-selectin (μg/L)

70 ± 37

82 ± 47

NS

  1. NS not significant, % percentage positive cells (either fibrinogen or P-selectin), TRAP-6 thrombin receptor activating peptide.